Animal Models in Cancer Research and Human Disease
Series: | |
Publisher: | Nova Biomedical/Nova Science Publishers, Inco |
Subject: | Disease--Animal models, Cancer research--Animal Models |
Authors: | Sean A. Murray |
Pages: | 152 pages |
Binding: | Hardcover |
ISBN: | 9781624175879 |
Call No: | RC280 B7 A55 2013 |
This book discusses the applications, outcomes and controversies of using animal models in cancer research and human disease. Topics include murine models of sporadic and inflammation-related colon carcinogenesis with particular focus on the AOM/DSS chemically induced colorectal cancer model; large animal models of human cardiovascular disease; developments of cell therapeutic strategies for Alzheimer's disease using animal models; the techniques and limitations of murine models of human colorectal cancer; animal models for antineoplastic chemotherapy-induced alopecia; and development of columnar-lined oesophagus with or without goblet cells in rate duodengastroesophageal reflux models through gut regenerative cell lineage (GRCL).