An Introduction to Human Molecular Genetics
| Series: | |
| Publisher: | John Wiley & Sons |
| Subject: | Human molecular genetics, Genetic disorders |
| Authors: | Jack J. Pasternak |
| Pages: | 676 pages |
| Binding: | Hardcover |
| ISBN: | 9780471474265 |
| Call No: | QH 431. P291 2005 |
The Second Edition of this internationally acclaimed text expands its coverage of the molecular genetics of inherited human diseases with the latest research findings and discoveries. Using a unique, systems-based approach, the text offers readers a thorough explanation of the gene discovery process and how defective genes are linked to inherited disease states in major organ and tissue systems. All the latest developments in functional genomics, proteomics, and microarray technology have been thoroughly incorporated into the text.
The first part of the text introduces readers to the fundamentals of cytogenetics and Mendelian genetics. Next, techniques and strategies for gene manipulation, mapping, and isolation are examined. Readers will particularly appreciate the text's exceptionally thorough and clear explanation of genetic mapping. The final part features unique coverage of the molecular genetics of distinct biological systems, covering muscle, neurological, eye, cancer, and mitochondrial disorders.