Drug Discovery and Development, Volume 1
| Series: | |
| Publisher: | Wiley |
| Subject: | Drug development, Drug evaluation, preclinical--Methods |
| Authors: | Mukund S. Chorghade |
| Pages: | 476 pages |
| Binding: | Hardcover |
| ISBN: | 9780471398486 |
| Call No: | RM 301.25 D794 2006 |
This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical practitioners.
- Includes case studies of the discovery of erythromycin analogs(antibiotics), Tagamet, and Ultiva (remifentanil)
- Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer
- Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemo genomics
The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and revising the drug as necessary.